2025
At the prestigious annual conference of the American Association for Cancer Research (AACR), an abstract from a paper by authors from Elphogene was presented under the title "A longitudinal investigation of temporal/intratumoral heterogeneity by plasma NGS profiling of mutation clones in metastatic colorectal cancer", which describes the newly observed phenomenon of the development of resistance to anticancer treatment within the framework of non-invasive liquid biopsy examination.
2024
As part of the traditional domestic conference Brno Oncology Days, a lecture was given entitled "Clinical significance of the dynamics of mutational clone development in plasma ctDNA during close monitoring of treatment of patients with solid tumors", delivered by assoc. Prof. Minárik from Elphogene. The paper presented unique results from clinical cases of patients undergoing non-invasive monitoring of tumor treatment at Elphogene.
Doc. Marek Minárik from Elphogene spoke at the international conference 6th Central-Eastern European congress on cfDNA. In a lecture entitled “Application of oncoMonitor liquid biopsy assay for monitoring of therapy and minimal residual disease in various solid cancers”, doc. Minárik presented the possibilities of applying oncoMonitor technology, which Elphogene provides for monitoring the treatment of cancer patients. During the first day of the conference, Prof. Dennis Lo, considered one of the most important pioneers of non-invasive diagnostics based on liquid biopsy, also spoke.
2022
The use of onkoMonitor technology for evaluating the success of surgical treatment and estimating the probability of lung cancer recurrence was presented at the 13th annual interdisciplinary oncology colloquium PragueONCO 2022. The lecture entitled "Circulating tumor DNA and bronchogenic carcinoma relapse" is based on a successful cooperation project between Elphogene, the Institute of Analytical Chemistry in Brno, and the Department of Thoracic Surgery of the 3rd Faculty of Medicine, Charles University and the Faculty of Medicine in Prague.
2021
At the Procision Diagnostics Europe virtual conference, Assoc. Prof. Minárik gave a lecture entitled "Developing a CE-based liquid-biopsy assay", in which the development and clinical validation of Elphogene's oncoMonitor methodology was presented.
At the January international conference PragueONCO, Assoc. Prof. Minárik presented a summary of current options for the application of the Elphogene onkoMonitor method. The lecture, titled "Clinical options for monitoring minimal residual disease using targeted liquid biopsy", was included in the section "Key developments in oncology research in the Czech Republic".
2020
The clinical use of oncoMonitor™ technology was presented at the AMP 2020 Annual Meeting & Expo of the Association for Molecular Pathology (AMP), which took place from 16 to 20 November 2020. Abstract number 877806 entitled “Clinical application of oncoMonitor - a simple method based on liquid biopsy that serves to monitor and assess the effectiveness of treatment for colorectal cancer and lung cancer” was selected for presentation in the form of a poster. Poster number ST01 was presented on November 19, 2020 in the section "Solid tumors". The selected abstract will also be published as an online supplement in the November issue of The Journal of Molecular Diagnostics.
Marek Minarik, Ph.D. presented the clinical use of the oncoMonitor™ test at the "EACR Conference on Liquid Biopsies - Virtual Event" organized by the European Association for Cancer Research (EACR). This virtual conference took place from 18 to 19 November 2020. Poster presentation number 23 entitled "oncoMonitor™ - a simple ctDNA minimal residual disease monitoring technology" was presented in the virtual poster section on 19 November from 13:00 to 14:00 .
Marek Minarik, Ph.D. gave a lecture at the 17th postgraduate course "News in the diagnosis and treatment of colorectal cancer - part 1", which was organized by the Society for Gastrointestinal Oncology and the Military University Hospital in Prague. The online course took place on November 5, 2020. In the "Diagnostics" section, Marek Minarik, Ph.D. presented a lecture entitled "New possibilities of non-invasive molecular examination of colorectal cancer".
Researchers from Elphogene, Inc. presented the clinical use of the oncoMonitor™ test at the "AACR Virtual Annual Meeting II" organized by the American Association for Cancer Research. This virtual conference took place from 22 to 24 June 2020 and Doc. Marek Minarik presented the latest data from clinical studies in patients with metastatic colorectal cancer in the form of poster presentation number 724 entitled "Application of oncoMonitor™ ctDNA tracking technology for monitoring of therapy and early detection of recurrence in metastatic colorectal cancer" in the Poster section "Circulating Markers 1 ".
Researchers from Elphogene, Inc. attended the "11th Prague interdisciplinary oncology colloquium PragueONCO 2020" from 29 to 31 January 2020 at Clarion Congress Hotel Prague. At the colloquium, which was held under the motto: “Doctors and nurses of various disciplines together against malignant tumors”, Marek Minarik, PhD. has presented oncoMonitor™ technology by an oral lecture entitled "Clinical use of the oncoMonitor™ test to monitor the course of treatment, capture of treatment resistance and recurrence in patients with metastatic colorectal cancer and in patients with advanced non-small cell lung cancer".
Researchers from Elphogene, Inc. attended the "Advances in Liquid Biopsies" conference organized by the American Association for Cancer Research, which was held from 13 to 16 January 2020 in Miami, Florida, USA. Marek Minarik, PhD. presented the latest data from clinical studies using liquid biopsy-based onMonitor™ technology in lung cancer patients. Poster presentation number A30 entitled "Dynamics of ctDNA may serve as an early predictor of response to non-targeted chemotherapy of advanced lung cancer patients." was presented in Poster Section A on Tuesday, January 14, 2020, from 16:15 to 18:45 (Hilton Miami Downtown).
2019
Researchers from Elphogene, Inc. have presented the latest clinical study data using oncoMonitor™-based liquid biopsy technology for non-invasive monitoring of advanced colorectal and lung cancer patients
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at the 5th National congress on Colorectal Cancer, held from 13 o 14 December 2019 in Prague, Czech Republic,
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at the 23rd National Conference on DNA Diagnostics, held from 28 to 29 November 2019 in Brno, Czech Republic, and
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on XXVII. West Bohemian Pneumooncological Days, which took place from 7 to 8 November 2019 in Pilsen, Czech Republic.
Lectures entitled "Possibilities of evaluation of treatment effectiveness in advanced colorectal cancer", "Development and validation of the oncoMonitor test for the detection of molecular residual disease and early prediction of solid tumor recurrence", and "Study on the possibility of using the oncoMonitor test for monitoring and predicting the effectiveness of non-targeted treatment of patients with advanced non-small cell lung cancer" were presented by Marek Minarik, Ph.D.
Other presentations at international conferences 2018-2019
Minarik M., Halkova T., Semyakina A., Belsanova B., Pudil J., Pazdirek F., Levy M., Simsa J., Hoch M., Ryska M., Benesova L. Annual Meeting of the AACR, Atlanta, GA, MAR 29-APR 03, 2019. Abstract 405: Using a ctDNA liquid biopsy assay for post-surgical serial monitoring and early detection of disease progression in advanced colorectal cancer patients. Cancer Res 2019;79(13) (Suppl).
Minark M., Svaton M., Belsanova B., Semyakina A., Baxa J., Fiala O., Pesek M., Benesova L. Annual Meeting of the AACR, Atlanta, GA, MAR 29-APR 03, 2019. Abstract 412: Application of a serial liquid biopsy ctDNA assay for monitoring efficacy of anti-angiogenic lung cancer therapy. Cancer Res 2019;79(13) (Suppl).
Pazdirek F., Stepanek L., Minarik M., Halkova T., Benesova L., Hoch J. 12th European Colorectal Congress 2018, DEC 03-06, 2018, St. Gallen, Switzerland.
