Scientists from Elphogene and the Genomac Research Institute in collaboration with leading Czech oncology centers have published an article in the international scientific journal World Journal of Gastroenterology.
The article entitled "Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating DNA tumor" was published on December 28, 2019 and summarizes the results of ctDNA analysis in 47 patients with metastatic colorectal cancer. The main outcome of this article is that ctDNA detection in patients with metastatic colorectal cancer is a viable tool for early detection of disease recurrence as well as for confirmation of the radicality of surgical treatment.
Ref.: Benesova L, Halkova T, Ptackova R, Semyakina A, Menclova K, Pudil J, Ryska M, Levy M, Simsa J, Pazdirek F, Hoch J, Blaha M and Minarik M. Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating tumor DNA. World J Gastroenterol. 2019, 25(48), 6939-6948.
Other publications in international scientific journals
Benesova L, Belsanova B, Minarikova P, Suchanek S, Kopeckova M, Levy M, Lipska L, Visokai V, Zavoral M, Minarik M. Mutation-based detection and monitoring of cell-free tumor DNA in peripheral blood of cancer patients. Anal Biochem. 2013, 433, 227-234.
Levy M, Benesova L, Lipska L, Belsanova B, Minarikova P, Veprekova G, Zavoral M, Minarik M. Utility of Cell-free Tumour DNA for Post-surgical Follow-up of Colorectal Cancer Patients. Anticancer Res. 2012, 32, 1621-1626.
Pesek M., Benesova L., Kopeckova M., Belsanova B., Fiala O., Minarik M. Options for testing DNA mutations and DNA methylation assays of circulating cell-free DNA isolated from peripheral blood of NSCLC patients. Studia Pneumologica et Phthiseologica. 2012, 72, 137-141.